2 Werdnig – Hoffmann disease

Reactions: 

Location of neurons affected by spinal muscular atrophy in the spinal cord

Werdnig – Hoffmann disease = SMA type I (Infantile)

  • Autosomal Recessive.
  • Usual age of onset : 0-6months
  • Marked hypotonia, Sluggish movement and fasciculation of tongue (Floppy Neonate).
  • Atrophy of spinal anterior horn cells.
  • Sparing : Extraoccular muscles and sphincters.
  • Death by 2-4yr age




Dubowitz disease = SMA type II (Intermediate)

Kugelberg – Welander disease = SMA type III (juvenile)


Adult onset - Type IV



Img source: http://en.wikipedia.org/wiki/File:Polio_spinal_diagram.PNG

2 comments:

Ask your doubts / point out towards any error / show appreciation / explain anything you wish to.

Related Posts Plugin for WordPress, Blogger...
To Search for a "particular word" on "the page on your screen" , press Ctrl + F and then type the word you need to search on the visible page.

eg: If you need to search the word "Anatomy" on this page -- Press "Ctrl + F" , (a box will appear) and then type Anatomy in the box that has appeared.