0 2bp insertion in middle of intron

What is the most likely effect of a 2bp insertion in the middle of the intron?
1. Normal transcription, altered translation.
2. Defective termination of transcription, normal translation.
3. Normal transcription, defective mRNA splicing.
4. Normal transcription, normal translation.

ANSWER:

Answer is A>D.
If the 2 bp insertion affects the translational regulatory elements , it will affect translation ; but if does not affect the translational regulatory elements , it will not affect translation. So ideally both ans a & d are right , but if to choose one - its better to go for A

0 AIIMS nov 2010 biochem

 1.Lactic acidosis is caused by which vitamin def
a) thiamine
b) riboflavin
c) niacin
d) pantothenic acid

ANSWER:

ans: A thiamine

2.What prevents ADP from leaving the mitochondria in exchange for ATP? 

a) oligomycin
b) rotenone
c) antimycin a
d) atractyloside

ANSWER:

ans:D atractyloside

3. Duchhene muscular dystrophy gene has a promoter site mutation, subsequent problem is? 

a) initiation of transcription is defective
b) capping of protein is defective 

c) tailing is defective
d) premature termination 

ANSWER:

ans:A initiation defective