2 Neuromuscular-blocking drugs

Neuromuscular-blocking drugs

These drugs fall into two groups:
  • Non-depolarizing blocking agents: These agents constitute the majority of the clinically relevant neuromuscular blockers. They act by competitively blocking the binding of ACh to its receptors, and in some cases, they also directly block the ionotropic activity of the ACh receptors.
  • Depolarizing blocking agents: These agents act by depolarizing the plasma membrane of the skeletal muscle fiber. This persistent depolarization makes the muscle fiber resistant to further stimulation by ACh.


  1. @Admin Thanks for such a useful web blog. I am a constant follower of your work.
    Can you please help to make some way on how to easily remember succinylcholine's DMR properties. I always confuse them and am afraid that if i make a mistake in a related direct question then it will cost me a lot in NEET PG or other exams.
    Thanks again in advance.

    1. Thanks for the kind words. We have conveyed your request to our content moderators.
      As of now DrAyushGoel informed us that he will soon (possibly by tonight or tomorrow morning ) be posting the desired article on Succinylcholine.


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