0 Local Anaesthetic Drugs - Important points

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Procaine :

  • 1-2% for nerve block
  • Metabolized by Pseudocholinesterase
  • LA of choice in Malignant Hyperthermia

Chloroprocaine :
  • Shortest acting
  • High pKa but still Fast acting (this is an exception)
  • Most acidic of all LA
  • Contraindicated for spinal anaesthesia

Lignocaine
  • 5% - heavy - spinal
  • 4% - Surface
  • 2% - Jelly for uretheral
  • 1-2% - Extradural
  • 1% - Nerve block
  • 0.5% - IVRA
  • Maximum safe dose : 3mg/kg ,( if with adrenaline - 7mg/kg)

Bupivacaine :
  • Long acting
  • Dose : 2mg/kg (max. safe dose) , ( if with adrenalin - 3mg/kg.)
  • Never IV


Prilocaine : 
  • S/E - Methemoglobenemia (T/t - Methylene blue)






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