0 Celiac disease

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Celiac disease ( Coeliac disease )
  • Gluten sensitivity 
    Thus if wheat is introduced in diet , there can be -
    1. Chronic Diarrhoea
    2. Recurrent diarrhoea
    3. Abdominal distention
    4. Vomiting
    5. Anorexia
    6. Failure to thrive
  • Can be asymptomatic
  • Age group : 6 months - 24 months


MCQ point - HLA DQ2 , DQ8

MARSH Criteria 
  1. Disease of small intestine in which
    - Villous atrophy
    - Crypt hyperplasia
    - Transmural inflammation
  2. If restrict gluten - mucosa returns to normal
  3. If gluten challenge - mucosa goes back to original state

Best Test :
  1. Anti Endomysial Antibody (Specificity 97 - 100%)
  2. Anti TTG (Tissue transglutaminase antibody )
Serum IgA levels are low

Treatment : Life long gluten restriction
i.e NO TO - Wheat , Barley and Rye.




MedicoNotebook - Founder : DrShiviMudgal , Co-Founder : DrAyushGoel

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