0 Infantile Spasms

Infantile Spasms (Salaam Seizures = West syndrome)

  • Onset at 4 - 8 months life.
  • Flexor Spasm (Symmetrical contracture of head trunk and extremities)
  • Rarely extensor or mixed
  • During sleep or arousal.

EEG - Hypsarrhythmia ( Chaotic pattern of high voltage bilateral synchronous waves)

Types : Idiopathic ; Secondary

Idiopathic = Cryptogenic ( Good prognosis )

Secondary -

  1. Birth asphyxia
  2. Structural malformations of brain
  3. Tuberous sclerosis
  4. Downs syndrome

Drug of choice : ACTH ( to suppress CRH - corticotropin releasing hormone)

DOC in cases of Tuberous sclerosis - Vigabatrin

MedicoNotebook - Founder : DrShiviMudgal , Co-Founder : DrAyushGoel

No comments:

Post a Comment

Ask your doubts / point out towards any error / show appreciation / explain anything you wish to.

Related Posts Plugin for WordPress, Blogger...
To Search for a "particular word" on "the page on your screen" , press Ctrl + F and then type the word you need to search on the visible page.

eg: If you need to search the word "Anatomy" on this page -- Press "Ctrl + F" , (a box will appear) and then type Anatomy in the box that has appeared.