0 Infantile Spasms

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Infantile Spasms (Salaam Seizures = West syndrome)


  • Onset at 4 - 8 months life.
  • Flexor Spasm (Symmetrical contracture of head trunk and extremities)
  • Rarely extensor or mixed
  • During sleep or arousal.


EEG - Hypsarrhythmia ( Chaotic pattern of high voltage bilateral synchronous waves)

Types : Idiopathic ; Secondary

Idiopathic = Cryptogenic ( Good prognosis )

Secondary -

  1. Birth asphyxia
  2. Structural malformations of brain
  3. Tuberous sclerosis
  4. Downs syndrome

Drug of choice : ACTH ( to suppress CRH - corticotropin releasing hormone)


DOC in cases of Tuberous sclerosis - Vigabatrin



MedicoNotebook - Founder : DrShiviMudgal , Co-Founder : DrAyushGoel

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