0 Cornea

Cornea


  • 45 - 50 D ,
  • 1.37 RI , 
  • 10.5 - 11 mm Diameter
Megalocornea - >13
Microcornea - <10

Shape - Asymmetrical

5 Layers - 
  • Epithelial (Proliferates)
  • Bowman's
  • Stroma
  • Descemet's membrane
  • Endothelium (NEVER DIVIDES) - Corneal Dehydration because of :
                                                 1. Na K ATPase pump - therefore does not allow hydration
                                                 2. also it is barrier
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Endothelial Cells - approx. 2500 cells/mm sq
When dies - there is compensation of space and function.
but if <500 cell/mm sq - then there will be no compensation -- i.e Corneal Decompensation -- Later leads to Bullous Keratopathy

Endothelium is metabolically most active.


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Contact Lens -- Decrease oxygen --- therefore decrease glucose utilization.


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