0 Medical One Liners 131 - 140

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131. Cat eye syndrome :
  • Partial trisomy of chromosome 22
  • Vertical oval pupil due to inferior iris coloboma
132. Single S2 in Tetrology of fallot.

133. All newborns have right ventricular hypertrophy and right axis deviation.

134. AA which have a pKa of 4 - aspartic acid and glutamic acid

135. Topoisomerase I (relaxase) 
  • makes ssDNA cuts, 
  • requires no ATP, 
  • relaxes supercoils, and 
  • acts as the swivel in front of the replication fork
136. 10 ATPs are generated per acetylCoA. (3NADH + 1FADH2 + 1GTP) {NADH = 2.5ATP; FADH2 = 1.5ATP}

137. Ketogenic AAs - Leucine and Lysine

138. Thiamine pyrophosphate (TPP) associated enzymes :
  • Alpha-ketoglutarate dehydrogenase
  • Pyruvate dehydrogenase
  • Transketolase
139. DNA replication occurs during S phase of the cell cycle.

140. Rise in conjugated (direct) bilirubin seen in Rotor syndrome and Dubin–Johnson syndrome.



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