0 Atrial Septal Defect (ASD)



Atrial Septal Defect (ASD)


  • MC- Secundum (Center)
  • Primum (big on medial side)
  • Sinus Venosus (at insertion of SVC, IVC)

Seen in 
  • Down's Syndrome
  • Lutembacher's syndrome ( ASD + MS/MR)
  • Ellis van creveld syndrome ( ASD + Polydactyly)
  • Holt oram syndrome ( Autosomal Dominant )
Holt Oram Syndrome = Hand heart syndrome : 
  1. Familial ASD syndrome
  2. With - VSD , Primary heart block , Atrial fibrillation, Bony Abnormality ( Thumb - absent / rudimentary)
  3. Pleiotropy - Multiple effects due to defect in single gene ( here TBX5)
  4. Can have absent radius.

ASD Secundum :
1. Asymptomatic
2. S2 - Wide and fixed split
3. Grows up - Adult - 
  • CHF
  • Arrhythmias
  • Stroke
  • Eisenmenger syndrome

ECG : Right axis deviation.

Treatment : Closure at 3-5yrs age by Dacron Patch

ASD Primum :

1. Big cleft on the medial side
2. Also has MR (always)

  • Pansystolic at Apex
  • Radiate to axila and back
3. S2 - Wide and fixed split
4. It is severe ASD
        therefore
      Clinical features at 6 - 10 wks
  • Failure to thrive
  • Recurrent infections
  • Feeding difficulties
  • CHF
ECG : Left axis deviation.

Treatment : Early surgery.




MedicoNotebook - Founder : DrShiviMudgal , Co-Founder : DrAyushGoel

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