0 Hamodalysis associated amyloid

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Q. Hamodalysis associated amyloid is deposited in
a. Synovium
b. Liver
c. Kidney
d. Tongue



ANSWER:
Ans: A.. Synovium.
The inability of both cuprophane dialysis
membranes to filter, and renal failure patients to catabolize
the plasma protein Beta-2 microglobulin, results in the accumulation
and subsequent conversion of this substance to
amyloid fibrils. Amyloid is deposited predominantly in the
musculoskeletal system in synovial, articular and periarticular
tissue, resulting in a variety of conditions.

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